Lil Wayne has reportedly been taken to hospital after suffering a seizure and being found unconscious in his hotel room in Chicago.
Celebrity website TMZ says the 34-year-old rapper, who has epilepsy, suffered a number of fits and had another one after arriving at A&E.
He had been due to perform in Las Vegas on Sunday night.
The rap star, whose real name is Dwayne Michael Carter Jr, was treated a year ago after suffering two minor seizures.
Four years ago Lil Wayne spent several days at a hospital in Los Angeles.
After those seizures the rapper told radio station Power 106 that he was epileptic and prone to having fits.
He told DJ Felli Fel: “This wasn’t my first, second, third, fourth, fifth, sixth, seventh…I have had a bunch of seizures, you just never hear about them.”
Lil Wayne says he suffers seizures because of stress, lack of rest and overworking himself.
Worried fans have been tweeting #prayforweezy after his latest seizures were reported.